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Introducing Agentic BLAST

Open-Core · GPLv3 · v1.0.0

Nexus-G Open-Core Intelligence Platform

A bioinformatics and agentic AI platform built for clinical genomics, eDNA research, and institutional data workflows — engineered at Vesta Gambit by Intechgambit LLC.

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~90%
Agentic BLAST faster
vs NCBI BLAST
Local-first
Runs on your hardware
Uptime focus
100%
Reproducible results
Reproducibility
// Download

Download Nexus-G

Free desktop installers for Windows and macOS. Confirm your email once — we log downloads for usage metrics and updates (no Stripe required).

Confirm email, then choose an installer below.

Windows

Pick the architecture of your PC (Settings → System → About).

  • Windows x64

    Intel / AMD 64-bit · .exe · v1.0.0

    Coming soon

  • Windows ARM64

    Snapdragon / ARM PCs · .exe · v1.0.0

    Coming soon

macOS

Apple menu → About This Mac. Apple Silicon is M1 and later.

  • macOS Intel

    Intel Mac · .dmg · v1.0.0

    Coming soon

  • macOS Apple Silicon

    M1 / M2 / M3 / M4 · .dmg · v1.0.0

    Coming soon

Open-core source: github.com/Intechgambit/nexus-g-core

// Use Cases

Built for real scientific workflows

From bench to enclave — Nexus-G powers reproducible pipelines across the most demanding research environments.

Clinical Genomics

HIPAA

End-to-end sequence analysis with enrichment, ML arbitration, and auditable reporting inside a controlled workspace.

Local-first + hybrid cloud

eDNA Research

Field Science

Environmental DNA metabarcoding pipelines for biodiversity monitoring, co-developed with Species Tracks LLC.

Metabarcoding + Agentic BLAST

Federal Data Workflows

Compliance-ready

Local, private cloud, or air-gapped deployments with reproducible workflows and institutional training paths.

Enterprise air-gap option
// Resources Hub

Open codebase & cloud infrastructure

intechgambit/nexus-g

GPLv3
~1M+
Entrez downloads · records retrieved
~100+
Task handlers · workflow & pipeline tasks
20+
ML models · arbitration, clustering, prep

$ nexus-g pipeline run

✓ ~100+ task handlers available

latest release v1.0.0

dual-license · community GPLv3 / enterprise commercial

Standard pipeline

Standard

Conversion, trimming + filtering, denoising, cluster, then ML-Predictor BLAST. Users can create unlimited custom pipelines and insert their own tools and code via the Pipeline Agent wizard.

Conversion
Trimming + Filtering
Denoising
Cluster
ML-Predictor BLAST

Reads are converted, trimmed and filtered, denoised, clustered, then scored with ML-Predictor BLAST. Your pipelines can still chain any installed tools, custom scripts, and format handoffs — not limited to this stage list.

NG-Cloud Compute & Storage

Compute Fabric

Local-first + NG-Cloud Batch hybrid

Hosted Databases

NG-Cloud NCBI stream to local workers

Storage Tier

BYOS + NG-Cloud hosted caps

Region Coverage

NG-Cloud regions & private GovCloud

// Product Ecosystem

How Nexus-G fits the ecosystem

Every product originates in Vesta Gambit, our sustainable green computing lab, and grows under the Gambit Nexus family.

Vesta Gambit

Green Computing Lab

Sustainable origin lab where all Intechgambit products are engineered.

Origin lab

Gambit Nexus

The product family spanning healthcare, agentic platforms, and emerging apps.

Live

Healthcare / Bioinformatics

Gambit Nexus (Nexus-G) — clinical genomics & agentic pipelines.

Beta

AD-Platform

Agentic decisioning platform for autonomous research operations.

R&D

Apps in Development

Next-gen tools incubating within the Gambit Nexus product family.